4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine
4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine
CAS: 174713-63-4
Molecular Formula: C12H10N4
4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine - Names and Identifiers
4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine - Physico-chemical Properties
| Molecular Formula | C12H10N4 |
| Molar Mass | 210.23 |
| Melting Point | 262-264°C |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD03001275 |
4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Class | IRRITANT |
4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine - Introduction
4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine (4-phenyl-1H-pyrazolo [3,4-b]pyridin-3-ylamine) is an organic compound. Its molecular formula is C16H13N5 and its molecular weight is 279.30g/mol.
The nature of the compound is solid, with white to light yellow particles. It is soluble in some organic solvents, such as ethanol and dimethyl sulfoxide. The compounds can be used as intermediates or starting materials in organic synthesis reactions.
In the field of drug development, 4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine is widely used to synthesize biologically active compounds. For example, it can be used to synthesize anti-tumor, anti-inflammatory, anti-viral and other drug molecules.
There are various approaches to the preparation of 4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine. One commonly used method is by reacting 4-amino-1H-pyrazole-3-ethanol with bromobenzene to give 4-chloro-1H-pyrazole-3-ethanol, which is then coupled with 5-amino-2-phenylpyridine to give 4-chloro-1H-pyrazolo [3,4-b] pyridine. Finally, 4-chloro-1H-pyrazolo [3,4-b] pyridine was reacted with phenylboronic acid by using a salt-based catalyst to give the final product 4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine.
Regarding the safety information of this compound, because there is no specific literature report, it is impossible to provide detailed safety information. However, as a chemical substance, it should be handled and used in accordance with routine laboratory safety procedures and be equipped with appropriate personal protective equipment. During use, care should be taken to avoid contact with skin, eyes and inhalation of its dust. In the event of unintentional exposure or accidental ingestion of the compound, medical attention should be sought immediately.
The nature of the compound is solid, with white to light yellow particles. It is soluble in some organic solvents, such as ethanol and dimethyl sulfoxide. The compounds can be used as intermediates or starting materials in organic synthesis reactions.
In the field of drug development, 4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine is widely used to synthesize biologically active compounds. For example, it can be used to synthesize anti-tumor, anti-inflammatory, anti-viral and other drug molecules.
There are various approaches to the preparation of 4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine. One commonly used method is by reacting 4-amino-1H-pyrazole-3-ethanol with bromobenzene to give 4-chloro-1H-pyrazole-3-ethanol, which is then coupled with 5-amino-2-phenylpyridine to give 4-chloro-1H-pyrazolo [3,4-b] pyridine. Finally, 4-chloro-1H-pyrazolo [3,4-b] pyridine was reacted with phenylboronic acid by using a salt-based catalyst to give the final product 4-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine.
Regarding the safety information of this compound, because there is no specific literature report, it is impossible to provide detailed safety information. However, as a chemical substance, it should be handled and used in accordance with routine laboratory safety procedures and be equipped with appropriate personal protective equipment. During use, care should be taken to avoid contact with skin, eyes and inhalation of its dust. In the event of unintentional exposure or accidental ingestion of the compound, medical attention should be sought immediately.
Last Update：2024-04-09 21:00:56
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